INT164251

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Context Info
Confidence 0.34
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrl, Gnrh1) extracellular region (Ghrl, Gnrh1) molecular_function (Gnrh1)
cytoplasm (Ghrl)
Ghrl (Rattus norvegicus)
Gnrh1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
narcan 4 99.74 Very High Very High Very High
Opioid 2 86.28 High High
antagonist 2 86.00 High High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hypothalamic Ghrelin suppresses pulsatile secretion of luteinizing hormone via beta-endorphin in ovariectomized rats.
Ghrelin Negative_regulation (suppresses) of Localization (secretion) of luteinizing hormone associated with narcan
1) Confidence 0.34 Published 2009 Journal Neuroendocrinology Section Title Doc Link 19907132 Disease Relevance 0 Pain Relevance 0.22
CONCLUSION: Suppressive effect of intracerebroventricular injection of ghrelin on pulsatile LH secretion was mediated by beta-END, suggesting that hypothalamic ghrelin suppressed pulsatile gonadotropin-releasing hormone secretion via beta-END in female rats.


ghrelin Negative_regulation (suppressed) of Localization (secretion) of gonadotropin-releasing hormone
2) Confidence 0.30 Published 2009 Journal Neuroendocrinology Section Body Doc Link 19907132 Disease Relevance 0 Pain Relevance 0

General Comments

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