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Context Info
Confidence 0.43
First Reported 1991
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.50
Pain Relevance 1.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Csf2) extracellular region (Csf2)
Anatomy Link Frequency
macrophage 2
frontal cortex 2
Csf2 (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 29 100.00 Very High Very High Very High
Glutamate 17 99.44 Very High Very High Very High
Morphine 8 99.38 Very High Very High Very High
Opioid 4 85.28 High High
narcan 2 70.72 Quite High
GABA receptor 1 69.72 Quite High
anesthesia 1 64.32 Quite High
imagery 4 58.32 Quite High
cerebral cortex 2 57.76 Quite High
GABAergic 2 42.32 Quite Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 1 97.60 Very High Very High Very High
Epilepsy 10 96.92 Very High Very High Very High
Tonic-clonic Epilepsy 1 89.56 High High
Cerebral Palsy 43 88.64 High High
Generalized Anxiety Disorder 17 86.44 High High
Stiff-person Syndrome 2 86.16 High High
Syndrome 14 84.24 Quite High
Ataxia 5 82.16 Quite High
Convulsion 3 81.24 Quite High
Cleft Palate 4 72.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Bone marrow cells from mice implanted with morphine pellets for 72 h showed a 65% decrease in their response to macrophage colony stimulating factor (M-CSF).
Negative_regulation (decrease) of Positive_regulation (response) of M-CSF in macrophage associated with morphine
1) Confidence 0.43 Published 1991 Journal Eur. J. Pharmacol. Section Abstract Doc Link 1831136 Disease Relevance 0 Pain Relevance 0.75
Decreased levels of brain and CSF GABA, increased levels of CSF and cortical glutamate, and decreased levels of PLP in the frontal cortex, have been described in this condition.
Negative_regulation (Decreased) of Positive_regulation (increased) of CSF in frontal cortex associated with glutamate, gaba and urological neuroanatomy
2) Confidence 0.07 Published 2004 Journal BMC Neurol Section Body Doc Link PMC544830 Disease Relevance 1.50 Pain Relevance 0.45

General Comments

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