INT164271

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Context Info
Confidence 0.56
First Reported 2010
Last Reported 2010
Negated 2
Speculated 1
Reported most in Abstract
Documents 2
Total Number 4
Disease Relevance 4.16
Pain Relevance 2.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ltb4r) plasma membrane (Ltb4r) signal transducer activity (Ltb4r)
Anatomy Link Frequency
spinal 1
nerve 1
DRG 1
Ltb4r (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 60 99.68 Very High Very High Very High
Spinal cord 12 98.56 Very High Very High Very High
Peripheral nerve injury 6 97.08 Very High Very High Very High
Neuropathic pain 8 95.72 Very High Very High Very High
IPN 8 91.68 High High
rheumatoid arthritis 10 90.32 High High
Inflammation 20 88.44 High High
intrathecal 4 87.52 High High
imagery 2 84.64 Quite High
antagonist 4 81.36 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 62 99.68 Very High Very High Very High
Nervous System Injury 14 99.26 Very High Very High Very High
Neuropathic Pain 10 95.72 Very High Very High Very High
Inflammatory Pain 8 91.68 High High
Rheumatoid Arthritis 10 90.32 High High
Asthma 6 89.44 High High
Nociception 12 88.80 High High
Disease 2 88.80 High High
INFLAMMATION 20 88.44 High High
Pain 16 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BLT1 mRNA was expressed in spinal neurons.
Transcription (expressed) of BLT1 in spinal
1) Confidence 0.56 Published 2010 Journal Glia Section Abstract Doc Link 19908283 Disease Relevance 1.03 Pain Relevance 0.67
The mRNAs for BLT1 and CysLT2 mRNAs were expressed in the DRG, but not the BLT2 and CysLT1 mRNAs (Figure 1A).
Neg (not) Transcription (expressed) of BLT1 associated with dorsal root ganglion
2) Confidence 0.44 Published 2010 Journal Mol Pain Section Body Doc Link PMC2949724 Disease Relevance 1.12 Pain Relevance 0.61
We detected mRNAs for BLT1 and CysLT2 in the DRG, but not for BLT2 and CysLT1.
Neg (not) Transcription (detected) of BLT1 in DRG associated with dorsal root ganglion
3) Confidence 0.44 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2949724 Disease Relevance 0.94 Pain Relevance 0.58
Using the spared nerve injury (SNI) model in rats, we investigated the expression of LT synthases (5-lipoxygenase; 5-LO, Five lipoxygenase activating protein; FLAP, LTA4 hydrolase; LTA4h and LTC4 synthase; LTC4s) and receptors (BLT1, 2 and CysLT1, 2) mRNAs in the rat spinal cord.
Spec (investigated) Transcription (expression) of BLT1 in nerve associated with nervous system injury and spinal cord
4) Confidence 0.36 Published 2010 Journal Glia Section Abstract Doc Link 19908283 Disease Relevance 1.08 Pain Relevance 0.55

General Comments

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