INT164277

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Context Info
Confidence 0.47
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.69
Pain Relevance 1.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ltc4s) nuclear envelope (Ltc4s) lyase activity (Ltc4s)
endoplasmic reticulum (Ltc4s) nucleus (Ltc4s)
Anatomy Link Frequency
neurons 1
eosinophils 1
microglia 1
Ltc4s (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 4 87.80 High High
intrathecal 2 82.56 Quite High
Peripheral nerve injury 4 76.56 Quite High
antagonist 7 76.40 Quite High
aspirin 75 76.00 Quite High
Neuropathic pain 6 75.20 Quite High
allodynia 2 73.68 Quite High
IPN 2 71.16 Quite High
rheumatoid arthritis 3 69.80 Quite High
Inflammation 5 67.92 Quite High
Disease Link Frequency Relevance Heat
Asthma 133 96.28 Very High Very High Very High
Nervous System Injury 12 92.04 High High
Neuropathic Pain 8 75.20 Quite High
Inflammatory Pain 2 71.16 Quite High
Rheumatoid Arthritis 3 69.80 Quite High
Disease 5 68.28 Quite High
INFLAMMATION 6 67.92 Quite High
Bronchospasm 6 48.44 Quite Low
Eosinophilia 1 41.96 Quite Low
Rhinitis 6 34.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LTA4h and LTC4s mRNAs were expressed in both spinal neurons and microglia.
Transcription (expressed) of LTC4s in microglia
1) Confidence 0.47 Published 2010 Journal Glia Section Abstract Doc Link 19908283 Disease Relevance 1.04 Pain Relevance 0.66
LTA4h and LTC4s mRNAs were expressed in both spinal neurons and microglia.
Transcription (expressed) of LTC4s in neurons
2) Confidence 0.16 Published 2010 Journal Glia Section Abstract Doc Link 19908283 Disease Relevance 1.04 Pain Relevance 0.66
Semiquantitative studies by Sanak and colleagues of LTC4 synthase transcripts in peripheral blood eosinophils showed increased numbers of mRNA copies in individuals with AEA[64].
Transcription (transcripts) of LTC4 synthase in eosinophils associated with asthma
3) Confidence 0.09 Published 2008 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2868885 Disease Relevance 0.61 Pain Relevance 0.04

General Comments

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