INT164349

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 3.14
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (KRT8) structural molecule activity (KRT8) nucleus (KRT8)
cytoskeleton organization (KRT8) cytoplasm (KRT8)
Anatomy Link Frequency
neuron 1
KRT8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 2 78.40 Quite High
Disease Link Frequency Relevance Heat
Cleidocranial Dysplasia 98 98.92 Very High Very High Very High
Adamantinoma 80 98.92 Very High Very High Very High
Sarcoma 1 97.66 Very High Very High Very High
Chordoma 1 97.20 Very High Very High Very High
Synovial Sarcoma 1 97.00 Very High Very High Very High
Generaliased Trisomy 1 96.32 Very High Very High Very High
Cancer 8 86.28 High High
Disease 14 80.96 Quite High
Pain 2 78.40 Quite High
Amputation 2 54.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
According to a study on the antibodies against a subtype of cytokeratin by Hazelbag et al, cytokeratin (CK) in AD is different from synovial sarcoma, chordoma, or epithelial sarcoma.13 Benassi et al. insisted on a correlation between OFD and AD based on their results that showed positive CK19 and negative CK8 and CK18 staining in both OFD and AD cases.12 In a cytogenetic study, both OFD and AD have trisomies on chromosomes 7, 8, and 12.4,16
Positive_regulation (negative) of CK8 associated with sarcoma, adamantinoma, cleidocranial dysplasia, synovial sarcoma, generaliased trisomy and chordoma
1) Confidence 0.10 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628088 Disease Relevance 3.06 Pain Relevance 0
Clinical and histopathological data were reviewed and immunohistochemical analysis was performed for S100, CD56, neuron-specific enolase, epithelial membrane antigen, CK7, CK8, CK14, and CK20.
Positive_regulation (performed) of CK8 in neuron
2) Confidence 0.08 Published 2009 Journal Oral Surg Oral Med Oral Pathol Oral Radiol Endod Section Abstract Doc Link 19913727 Disease Relevance 0.08 Pain Relevance 0.08

General Comments

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