INT164362

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 7
Disease Relevance 2.37
Pain Relevance 4.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NLRP1, VTA1) cytoplasm (NLRP1, VTA1) endosome (VTA1)
nucleus (NLRP1) intracellular (NLRP1) enzyme binding (NLRP1)
Anatomy Link Frequency
NAc 3
hypothalamus 2
insula 2
NLRP1 (Homo sapiens)
VTA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 63 100.00 Very High Very High Very High
Nucleus accumbens 63 100.00 Very High Very High Very High
Ventral tegmentum 49 100.00 Very High Very High Very High
insula 14 99.04 Very High Very High Very High
Opioid 14 79.60 Quite High
agonist 14 78.88 Quite High
antagonist 7 78.60 Quite High
narcan 7 77.52 Quite High
addiction 7 25.00 Low Low
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 14 88.00 High High
Alcohol Addiction 7 84.16 Quite High
Syndrome 28 75.00 Quite High
Cognitive Disorder 7 66.40 Quite High
Drug Dependence 7 38.32 Quite Low
Mental Disorders 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus it is conjectured that similar mechanisms in terms of adequate dopamine release and subsequent activation of reward circuitry by listening to music might also be affected by an individual's D2 density in the VTA mediated interaction of the NAc.
NAc Binding (interaction) of VTA in NAc associated with nucleus accumbens, ventral tegmentum and dopamine
1) Confidence 0.15 Published 2010 Journal Med. Hypotheses Section Abstract Doc Link 19914781 Disease Relevance 0.44 Pain Relevance 0.85
Importantly, responses in the NAc and VTA were strongly correlated pointing to an association between dopamine release and NAc response to music.
NAc Binding (association) of VTA in NAc associated with ventral tegmentum, nucleus accumbens and dopamine
2) Confidence 0.13 Published 2010 Journal Med. Hypotheses Section Abstract Doc Link 19914781 Disease Relevance 0.28 Pain Relevance 0.60
Listing to pleasant music induced a strong response and significant activation of the VTA-mediated interaction of the NAc with the hypothalamus, insula, and orbitofrontal cortex.
NAc Binding (interaction) of VTA in insula associated with nucleus accumbens, ventral tegmentum and insula
3) Confidence 0.11 Published 2010 Journal Med. Hypotheses Section Abstract Doc Link 19914781 Disease Relevance 0.30 Pain Relevance 0.59
Thus it is conjectured that similar mechanisms in terms of adequate dopamine release and subsequent activation of reward circuitry by listening to music might also be affected by an individual's D2 density in the VTA mediated interaction of the NAc.
NAc Binding (interaction) of VTA in NAc associated with nucleus accumbens, ventral tegmentum and dopamine
4) Confidence 0.11 Published 2010 Journal Med. Hypotheses Section Abstract Doc Link 19914781 Disease Relevance 0.44 Pain Relevance 0.85
Listing to pleasant music induced a strong response and significant activation of the VTA-mediated interaction of the NAc with the hypothalamus, insula, and orbitofrontal cortex.
NAc Binding (interaction) of VTA in insula associated with nucleus accumbens, ventral tegmentum and insula
5) Confidence 0.11 Published 2010 Journal Med. Hypotheses Section Abstract Doc Link 19914781 Disease Relevance 0.30 Pain Relevance 0.59
Listing to pleasant music induced a strong response and significant activation of the VTA-mediated interaction of the NAc with the hypothalamus, insula, and orbitofrontal cortex.
NAc Binding (interaction) of VTA in hypothalamus associated with nucleus accumbens, ventral tegmentum and insula
6) Confidence 0.04 Published 2010 Journal Med. Hypotheses Section Abstract Doc Link 19914781 Disease Relevance 0.30 Pain Relevance 0.59
Listing to pleasant music induced a strong response and significant activation of the VTA-mediated interaction of the NAc with the hypothalamus, insula, and orbitofrontal cortex.
NAc Binding (interaction) of VTA in hypothalamus associated with nucleus accumbens, ventral tegmentum and insula
7) Confidence 0.04 Published 2010 Journal Med. Hypotheses Section Abstract Doc Link 19914781 Disease Relevance 0.30 Pain Relevance 0.59

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox