INT164364

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Context Info
Confidence 0.06
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.33
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SUGT1) pigmentation (DRD2) mitosis (SUGT1)
plasma membrane (DRD2) signal transducer activity (DRD2)
DRD2 (Homo sapiens)
SUGT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 12 99.62 Very High Very High Very High
insula 2 95.64 Very High Very High Very High
Nucleus accumbens 9 94.44 High High
Catechol-O-methyltransferase 29 93.68 High High
Ventral tegmentum 7 93.16 High High
narcan 1 52.32 Quite High
Opioid 2 50.88 Quite High
antagonist 1 50.32 Quite High
addiction 2 25.00 Low Low
agonist 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Alcohol Addiction 1 99.48 Very High Very High Very High
Cognitive Disorder 2 81.20 Quite High
Syndrome 4 75.00 Quite High
Attention Deficit Hyperactivity Disorder 2 32.96 Quite Low
Drug Dependence 2 25.00 Low Low
Depression 10 5.00 Very Low Very Low Very Low
Severe Combined Immunodeficiency 4 5.00 Very Low Very Low Very Low
Personality Disorder 1 5.00 Very Low Very Low Very Low
Schizophrenia 1 5.00 Very Low Very Low Very Low
Manic Depressive Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Blum et al. [10] provided the first evidence that the dopamine D2 receptor gene (DRD2) Taq 1 A1 allele significantly associated with severe alcoholism whereby the author's suggested that they found the first "reward gene" located in the mesolimbic system.
DRD2 Binding (associated) of allele associated with alcohol addiction and dopamine
1) Confidence 0.06 Published 2010 Journal Med. Hypotheses Section Abstract Doc Link 19914781 Disease Relevance 0.33 Pain Relevance 0.66
Similarly, Noble et al. [10] found that DRD2, examined either as the TaqI A allele or as a haplotype, was not associated with HA.
DRD2 Binding (associated) of allele
2) Confidence 0.03 Published 2007 Journal Behav Brain Funct Section Body Doc Link PMC1779796 Disease Relevance 0 Pain Relevance 0.12

General Comments

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