INT164365

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Context Info
Confidence 0.14
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.60
Pain Relevance 1.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NLRP1, VTA1) cytoplasm (NLRP1, VTA1) endosome (VTA1)
nucleus (NLRP1) intracellular (NLRP1) enzyme binding (NLRP1)
Anatomy Link Frequency
insula 3
hypothalamus 1
NLRP1 (Homo sapiens)
VTA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Nucleus accumbens 18 100.00 Very High Very High Very High
Ventral tegmentum 14 100.00 Very High Very High Very High
insula 4 99.04 Very High Very High Very High
Dopamine 18 97.52 Very High Very High Very High
narcan 2 37.52 Quite Low
Opioid 4 36.08 Quite Low
antagonist 2 35.52 Quite Low
agonist 4 25.00 Low Low
addiction 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Alcohol Addiction 2 84.16 Quite High
Syndrome 8 75.00 Quite High
Cognitive Disorder 2 66.40 Quite High
Attention Deficit Hyperactivity Disorder 4 25.00 Low Low
Drug Dependence 2 25.00 Low Low
Mental Disorders 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Listing to pleasant music induced a strong response and significant activation of the VTA-mediated interaction of the NAc with the hypothalamus, insula, and orbitofrontal cortex.
Positive_regulation (induced) of NAc Binding (interaction) of VTA in insula associated with nucleus accumbens, ventral tegmentum and insula
1) Confidence 0.14 Published 2010 Journal Med. Hypotheses Section Abstract Doc Link 19914781 Disease Relevance 0.30 Pain Relevance 0.60
Listing to pleasant music induced a strong response and significant activation of the VTA-mediated interaction of the NAc with the hypothalamus, insula, and orbitofrontal cortex.
Positive_regulation (induced) of NAc in hypothalamus Binding (interaction) of VTA in insula associated with nucleus accumbens, ventral tegmentum and insula
2) Confidence 0.05 Published 2010 Journal Med. Hypotheses Section Abstract Doc Link 19914781 Disease Relevance 0.30 Pain Relevance 0.60

General Comments

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