INT164417

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Context Info
Confidence 0.34
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.71
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (CRLF1) extracellular region (CRLF1) plasma membrane (CRLF1)
cytoplasm (CRLF1)
Anatomy Link Frequency
skin 1
knee 1
CRLF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 1 100.00 Very High Very High Very High
visual analogue scale 8 99.92 Very High Very High Very High
Pain 17 98.86 Very High Very High Very High
Osteoarthritis 10 97.44 Very High Very High Very High
Demyelination 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 11 99.08 Very High Very High Very High
Pain 17 98.86 Very High Very High Very High
Hypesthesia 10 98.34 Very High Very High Very High
Syndrome 88 98.08 Very High Very High Very High
Hand Injuries 76 95.64 Very High Very High Very High
Arthropathy 1 94.20 High High
Carpal Tunnel Syndrome 2 86.44 High High
Nervous System Injury 10 85.28 High High
Injury 22 84.16 Quite High
Amputation 14 83.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cytokine receptor-like factor 1 is highly expressed in damaged human knee osteoarthritic cartilage and involved in osteoarthritis downstream of TGF-beta.
Gene_expression (expressed) of Cytokine receptor-like factor 1 in knee associated with osteoarthritis and cytokine
1) Confidence 0.34 Published 2010 Journal Calcif. Tissue Int. Section Title Doc Link 19921088 Disease Relevance 0.89 Pain Relevance 0.44
Self-reported cold sensitivity (CISS questionnaire, VAS question and PWES)
Gene_expression (questionnaire) of CISS associated with visual analogue scale
2) Confidence 0.05 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2881018 Disease Relevance 1.22 Pain Relevance 0.10
The predominant problems on exposure to cold among the patients were weakness, stiffness, numbness, skin colour change, pain and aching in their injured hands (Question no 1 in the CISS questionnaire, Fig 2).
Gene_expression (questionnaire) of CISS in skin associated with pain and hypesthesia
3) Confidence 0.05 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2881018 Disease Relevance 1.60 Pain Relevance 0.22

General Comments

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