INT164457

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (NTRK1) endosome (NTRK1) aging (Ngf)
extracellular space (Ngf) signal transduction (Ngf) extracellular region (Ngf)
Anatomy Link Frequency
ganglion 1
Ngf (Rattus norvegicus)
NTRK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Nerve growth factor 7 100.00 Very High Very High Very High
antagonist 3 87.92 High High
drug abuse 1 80.72 Quite High
depression 1 79.88 Quite High
Neuropathic pain 1 79.40 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 94.52 High High
Drug Dependence 1 80.72 Quite High
Depression 1 79.88 Quite High
Neuropathic Pain 1 79.40 Quite High
Disease 3 78.68 Quite High
Neurodegenerative Disease 1 75.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Y1036 prevents both BDNF- and NGF-mediated trk activation, downstream activation of the p44/42 mitogen-activated protein kinase pathway, and neurotrophin-mediated differentiation of dorsal-root ganglion sensory neurons.
NGF Positive_regulation (activation) of trk in ganglion associated with ganglion cysts and nerve growth factor
1) Confidence 0.15 Published 2010 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 19923440 Disease Relevance 0.57 Pain Relevance 0.58

General Comments

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