INT16446

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Context Info
Confidence 0.69
First Reported 1991
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.76
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (IL1A) cytosol (IL1A) extracellular space (IL1A)
extracellular region (IL1A)
IL1A (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 17 100.00 Very High Very High Very High
Pain 1 93.24 High High
Inflammation 86 88.40 High High
Inflammatory response 17 77.92 Quite High
pulpitis 2 75.00 Quite High
Snapping jaw 4 69.44 Quite High
Osteoarthritis 3 67.96 Quite High
tolerance 1 52.64 Quite High
Inflammatory stimuli 4 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 2 94.88 High High
Fever 1 94.48 High High
Urticaria 2 94.20 High High
Pain 1 93.24 High High
Disease 10 91.32 High High
INFLAMMATION 108 88.40 High High
Thymoma 1 84.76 Quite High
Pulpitis 2 75.00 Quite High
Macroglobulinemia 1 75.00 Quite High
Immunization 1 71.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mRNA levels of IL-1alpha, IL-1beta, IL-6, IL-8, and IL-18 were measured concomitantly by quantitative real-time RT-PCR.
Transcription (levels) of IL-1alpha
1) Confidence 0.69 Published 2003 Journal Cytokine Section Abstract Doc Link 12849707 Disease Relevance 0.25 Pain Relevance 0.37
The impact-loading induced the expression of IL-1beta immunohistochemically and prominently up-regulated IL-1alpha and IL-1beta mRNA levels in subchondral bone.
Transcription (levels) of IL-1alpha
2) Confidence 0.69 Published 2009 Journal Ann Biomed Eng Section Abstract Doc Link 19381811 Disease Relevance 0.34 Pain Relevance 0.25
In a screening of 271 sera, IL-1 alpha BF was detected in 17/98 normal subjects and was not more frequent in several control groups of patients, except in patients with Schnitzler's syndrome (fever, chronic urticaria, bone pain, and monoclonal IgM paraprotein) (6/9; p less than 0.005).
Transcription (detected) of IL-1 alpha associated with urticaria, pain, syndrome and fever
3) Confidence 0.50 Published 1991 Journal J. Allergy Clin. Immunol. Section Abstract Doc Link 1831824 Disease Relevance 0.76 Pain Relevance 0.09
B and activation of the transcription of various proinflammatory cytokines [13] (IL1A, IL1B, TNFA, IL6, IL8,...etc).
Transcription (transcription) of IL1A associated with cytokine
4) Confidence 0.23 Published 2008 Journal BMC Med Genomics Section Body Doc Link PMC2567339 Disease Relevance 0.40 Pain Relevance 0.25

General Comments

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