INT164513

Context Info Confidence 0.37 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.52 Pain Relevance 0

cytosol (EEA1) intracellular (EEA1) cytoplasm (EEA1)

EEA1 (Homo sapiens)

Pain Link Frequency Relevance Heat imagery 2 5.00 headache 2 5.00 Pain 1 5.00 cva 1 5.00

Disease Link Frequency Relevance Heat Infection 84 97.52 Viral Meningitis 3 76.44 Diarrhoea 1 75.04 Dengue 11 50.00 Central Nervous System Cysts 2 50.00 Dengue Hemorrhagic Fever 9 5.00 Targeted Disruption 4 5.00 Fever 3 5.00 Disease 3 5.00 Headache 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

CONCLUSIONS: The EEA is a safe and effective approach in the treatment of RCCs.

Regulation (effective) of EEA

1) Confidence 0.37 Published 2010 Journal J. Neurosurg. Section Body Doc Link 19929190 Disease Relevance 0 Pain Relevance 0

Our primary siRNA screen has also indicated that targeting of the endocytic trafficking proteins and associated kinases, Rab5A, Rab7, Rab11b, ELKS, early endosome antigen 1 and MAPK8IP2, each resulted in significant decreases in DENV infection (Figure 2 and Additional File 2).

Regulation (targeting) of early endosome antigen 1 associated with infection

2) Confidence 0.33 Published 2010 Journal Virol J Section Body Doc Link PMC2825209 Disease Relevance 0.52 Pain Relevance 0

General Comments

This test has worked.