INT164567

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.19
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

translation factor activity, nucleic acid binding (EIF1) translation (EIF1) response to stress (EIF1)
cytoplasm (EIF1)
Anatomy Link Frequency
blood 1
EIF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 1 99.12 Very High Very High Very High
adenocard 7 86.60 High High
antagonist 2 48.36 Quite Low
cINOD 1 48.36 Quite Low
Thalamus 12 31.28 Quite Low
Glutamate 4 5.00 Very Low Very Low Very Low
Action potential 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
GABA receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 99.12 Very High Very High Very High
Pleurisy 1 91.08 High High
Syndrome 4 5.00 Very Low Very Low Very Low
Convulsion 4 5.00 Very Low Very Low Very Low
Epilepsy 3 5.00 Very Low Very Low Very Low
Sleep Disorders 1 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To test whether a similar breakdown of ATP is responsible for shaping the thalamic ISO described in this study we examined the effect of the ecto-ATPase inhibitor, ARL 67156 (10 ┬ÁM), on the extracellularly-recorded ISO.
Negative_regulation (inhibitor) of ISO
1) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2637539 Disease Relevance 0 Pain Relevance 0.13
Taken together, these results indicate that YS121 is a promising inhibitor of mPGES-1 with anti-inflammatory efficiency in human whole blood as well as in vivo.
Negative_regulation (inhibitor) of YS121 in blood associated with inflammation
2) Confidence 0.01 Published 2010 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 19934399 Disease Relevance 0.19 Pain Relevance 0.05

General Comments

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