INT164729

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Context Info
Confidence 0.48
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 0.20
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Mgll) lipid metabolic process (Mgll)
Anatomy Link Frequency
brain 2
Mgll (Mus musculus)
Pain Link Frequency Relevance Heat
Endocannabinoid 30 98.32 Very High Very High Very High
agonist 6 93.84 High High
Cannabinoid receptor 12 93.36 High High
Pain 5 47.36 Quite Low
analgesia 3 5.00 Very Low Very Low Very Low
Inflammation 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 42 99.04 Very High Very High Very High
Pain 5 47.36 Quite Low
Obesity 3 41.92 Quite Low
Hypothermia 3 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 3 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Appetite Loss 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The developed methods were applied to study the hydrolysis of 2-AG from mouse brain extracts containing membrane bound monoacylglycerol lipase (MAGL), and to measure the basal levels of 2-AG, 1-AG and AA in mouse brain and adipose tissues.
monoacylglycerol lipase Binding (bound) of in brain
1) Confidence 0.48 Published 2010 Journal J Mass Spectrom Section Abstract Doc Link 19950120 Disease Relevance 0 Pain Relevance 0
The developed methods were applied to study the hydrolysis of 2-AG from mouse brain extracts containing membrane bound monoacylglycerol lipase (MAGL), and to measure the basal levels of 2-AG, 1-AG and AA in mouse brain and adipose tissues.
MAGL Binding (bound) of in brain
2) Confidence 0.47 Published 2010 Journal J Mass Spectrom Section Abstract Doc Link 19950120 Disease Relevance 0 Pain Relevance 0
To our knowledge, MGL was shown to bind to membrane structures and was never identified as LD-associated protein in mammalian cells so far.
MGL Binding (bind) of
3) Confidence 0.11 Published 2010 Journal Biochimica et Biophysica Acta Section Body Doc Link PMC2911655 Disease Relevance 0 Pain Relevance 0
lacks detectable MGL activity at pH 7.5 against rac-1(3)-OG, and hydrolysis of 2-OG was reduced by ? 
MGL Binding (activity) of
4) Confidence 0.08 Published 2010 Journal Biochimica et Biophysica Acta Section Body Doc Link PMC2911655 Disease Relevance 0.20 Pain Relevance 0
MGL was recognized in recent years as a potential player in EC metabolism [42]. 2-AG and anandamide (N-arachidonoylethanolamide; AEA) are considered as the main endogenous agonists of cannabinoid receptors [7].
MGL Binding (recognized) of associated with endocannabinoid, cannabinoid receptor and agonist
5) Confidence 0.08 Published 2010 Journal Biochimica et Biophysica Acta Section Body Doc Link PMC2911655 Disease Relevance 0 Pain Relevance 0.14

General Comments

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