INT164730

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.51
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
spinal cord 2
ecs (Mus musculus)
Pain Link Frequency Relevance Heat
Endocannabinoid 10 100.00 Very High Very High Very High
Cannabinoid receptor 2 99.84 Very High Very High Very High
Pain 1 98.72 Very High Very High Very High
Neuropathic pain 3 98.70 Very High Very High Very High
Spinal cord 2 96.56 Very High Very High Very High
Cannabinoid 2 69.52 Quite High
antagonist 4 67.36 Quite High
neuralgia 1 25.00 Low Low
anesthesia 1 25.00 Low Low
allodynia 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Pain 1 98.72 Very High Very High Very High
Neuropathic Pain 9 98.70 Very High Very High Very High
Nociception 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Levels of ECs are tightly controlled by enzymatic biosynthesis and degradation in vivo.
Regulation (controlled) of Gene_expression (Levels) of ECs associated with endocannabinoid
1) Confidence 0.22 Published 2010 Journal J Mass Spectrom Section Abstract Doc Link 19950120 Disease Relevance 0.10 Pain Relevance 0.24
Models of neuropathic pain are associated with elevated spinal levels of endocannabinoids (ECs) and altered expression of cannabinoid receptors on primary sensory afferents and post-synaptic cells in the spinal cord.
Regulation (altered) of Gene_expression (expression) of ECs in spinal cord associated with endocannabinoid, cannabinoid receptor, neuropathic pain and spinal cord
2) Confidence 0.03 Published 2010 Journal Eur. J. Neurosci. Section Abstract Doc Link 20384778 Disease Relevance 0.41 Pain Relevance 0.62

General Comments

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