INT164954

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Context Info
Confidence 0.36
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.85
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Adc)
Anatomy Link Frequency
brain 1
astrocytes 1
Adc (Mus musculus)
Pain Link Frequency Relevance Heat
ischemia 26 96.12 Very High Very High Very High
Glutamate 5 90.68 High High
Glutamate receptor 1 87.56 High High
Central nervous system 3 79.84 Quite High
cytokine 1 75.24 Quite High
Neuronal nitric oxide synthase 1 69.52 Quite High
imagery 16 65.28 Quite High
anesthesia 3 18.28 Low Low
cva 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 8 98.24 Very High Very High Very High
Injury 25 97.16 Very High Very High Very High
Brain Injury 6 96.40 Very High Very High Very High
Hypoxia 1 95.76 Very High Very High Very High
Death 1 94.72 High High
Cv General 4 Under Development 8 89.52 High High
Hemorrhage 3 85.36 High High
Necrosis 2 83.76 Quite High
Apoptosis 9 83.28 Quite High
Transient Ischemic Attack 9 67.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Acute ADC decrease is not specific of ischemic insult and has been described in both experimental and human traumatic brain injury [14,15].
Localization (decrease) of ADC in brain associated with brain injury
1) Confidence 0.36 Published 2010 Journal Exp Transl Stroke Med Section Body Doc Link PMC2827391 Disease Relevance 0.80 Pain Relevance 0.08
ADC, lambda(1), lambda(2), and lambda(3) increased significantly by clenching (P <0.01, P <0.01, P <0.01, and P <0.01, respectively) on both sides.
Localization (increased) of ADC
2) Confidence 0.31 Published 2010 Journal Acta Radiol Section Body Doc Link 20001471 Disease Relevance 0 Pain Relevance 0
Arginine decarboxylase, the enzyme responsible for synthesis of agmatine, is largely localized in astrocytes, so endogenous agmatine production is likely in astrocytes.
Localization (localized) of Arginine decarboxylase in astrocytes
3) Confidence 0.06 Published 2010 Journal BMC Pharmacol Section Body Doc Link PMC2941483 Disease Relevance 1.04 Pain Relevance 0.55

General Comments

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