INT165047

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Context Info
Confidence 0.73
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Mapk14) cell morphogenesis (Mapk14) intracellular (Tnf)
extracellular matrix organization (Tnf) response to stress (Mapk14) cytoplasm (Mapk14)
Mapk14 (Rattus norvegicus)
Tnf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 2 98.72 Very High Very High Very High
Neuropeptide 1 94.44 High High
Calcitonin gene-related peptide 8 93.92 High High
backache 1 91.76 High High
dorsal root ganglion 6 86.64 High High
Root ganglion neuron 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Pain 2 98.72 Very High Very High Very High
Necrosis 1 95.28 Very High Very High Very High
Cancer 1 94.92 High High
Low Back Pain 1 91.76 High High
Ganglion Cysts 7 86.64 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because p38 mitogen-activated protein kinase (p38) upregulates TNF-alpha expression and may play a crucial role in pain sensation, we investigated the effect of one injection of inhibitor on expression of the pain-related neuropeptide calcitonin gene-related peptide (CGRP).
p38 Positive_regulation (upregulates) of Gene_expression (expression) of TNF-alpha associated with pain, neuropeptide and calcitonin gene-related peptide
1) Confidence 0.73 Published 2009 Journal Spine Section Abstract Doc Link 20010392 Disease Relevance 0.80 Pain Relevance 0.63

General Comments

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