INT165060

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Context Info
Confidence 0.68
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SLC29A4) transmembrane transport (SLC29A4)
Anatomy Link Frequency
CNS 1
SLC29A4 (Homo sapiens)
Pain Link Frequency Relevance Heat
monoamine 8 97.40 Very High Very High Very High
Neurotransmitter 2 96.60 Very High Very High Very High
depression 1 94.24 High High
Central nervous system 3 90.76 High High
antidepressant 4 75.00 Quite High
Desipramine 1 60.56 Quite High
Endep 1 59.52 Quite High
fluoxetine 1 57.44 Quite High
Disease Link Frequency Relevance Heat
Depression 1 94.24 High High
Schizophrenia 1 93.64 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, the PMAT which is highly expressed in the human brain may be involved in the modulation of central monoaminergic neurotransmission and it may be a target for drugs used to treat depression and schizophrenia, i.e., dysregulations of the monoamine homeostasis in the central nervous system (CNS).
Gene_expression (expressed) of PMAT in CNS associated with depression, central nervous system, schizophrenia and monoamine
1) Confidence 0.68 Published 2010 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 20012264 Disease Relevance 0.19 Pain Relevance 0.81

General Comments

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