INT165149

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Context Info
Confidence 0.42
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ihh) peptidase activity (Ihh) extracellular region (Ihh)
plasma membrane (Ihh) embryo development (Ihh) cell-cell signaling (Ihh)
Ihh (Mus musculus)
Pain Link Frequency Relevance Heat
Potency 1 71.68 Quite High
antagonist 1 45.52 Quite Low
Enkephalin 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Aplasia 1 92.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Analyses of activated IHH signaling in C3H10T1/2 cells showed that three BDA1-associated mutations (p.E95K, p.D100E and p.E131K) severely impaired the induction of targets such as Ptch1 and Gli1.
Positive_regulation (activated) of IHH
1) Confidence 0.42 Published 2010 Journal Cell. Mol. Biol. Lett. Section Abstract Doc Link 20024692 Disease Relevance 0.09 Pain Relevance 0.04

General Comments

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