INT165179

Context Info Confidence 0.15 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.95 Pain Relevance 0

cytosol (ABL1) protein modification process (ABL1) mitochondrion (ABL1) nucleolus (ABL1) nucleus (ABL1) DNA binding (ABL1)

Anatomy Link Frequency lung 2 ABL1 (Homo sapiens)

Pain Link Frequency Relevance Heat Analgesic 1 25.00

Disease Link Frequency Relevance Heat Cancer 3 98.92 Lung Cancer 1 98.04 Non-small-cell Lung Cancer 4 97.08 Leukemia 1 96.64 Myeloid Leukemia 4 95.60 Death 2 59.60 Apoptosis 1 54.08

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Deregulated activation of protein tyrosine kinases, such as the epidermal growth factor receptor (EGFR) and Abl, is associated with human cancers including non-small cell lung cancer (NSCLC) and chronic myeloid leukemia (CML).

Regulation (Deregulated) of Positive_regulation (activation) of Abl in lung associated with leukemia, myeloid leukemia, lung cancer, non-small-cell lung cancer and cancer

1) Confidence 0.15 Published 2010 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 20026060 Disease Relevance 0.95 Pain Relevance 0

General Comments

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