INT165622

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Context Info
Confidence 0.14
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.54
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TGS1) nucleoplasm (TGS1) small molecule metabolic process (TGS1)
methyltransferase activity (TGS1) nucleus (TGS1) cytoplasm (TGS1)
Anatomy Link Frequency
plasma 2
TGS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
abdominal pain 1 90.44 High High
tolerance 8 85.68 High High
cva 8 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 15 99.40 Very High Very High Very High
Xanthomatosis 1 92.72 High High
Pancreatitis 2 91.24 High High
Abdominal Pain 1 90.44 High High
Hyperlipidemia 3 89.16 High High
Impaired Glucose Tolerance 8 86.32 High High
Congenital Anomalies 3 81.84 Quite High
Metabolic Syndrome 12 69.92 Quite High
Obesity 11 69.04 Quite High
Diabetes Mellitus 17 66.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The desirable level for TGs is defined as <200, moderate risk as 200–400, and high risk as ?
Negative_regulation (defined) of Gene_expression (level) of TGs
1) Confidence 0.14 Published 2009 Journal Trials Section Body Doc Link PMC2656492 Disease Relevance 0.94 Pain Relevance 0.04
The LPLSer(447)X variant is associated with decreased levels of plasma TGs and increased HDL cholesterol concentrations compared with wild-type LPL.
Negative_regulation (decreased) of Gene_expression (levels) of TGs in plasma associated with disorder of lipid metabolism
2) Confidence 0.04 Published 2009 Journal Curr. Opin. Mol. Ther. Section Abstract Doc Link 20072945 Disease Relevance 0.60 Pain Relevance 0.09

General Comments

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