INT165623

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Context Info
Confidence 0.22
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.42
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (TGS1) nucleoplasm (TGS1) small molecule metabolic process (TGS1)
methyltransferase activity (TGS1) nucleus (TGS1) cytoplasm (TGS1)
Anatomy Link Frequency
plasma 1
TGS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
abdominal pain 1 90.04 High High
tolerance 16 84.80 Quite High
cva 16 5.00 Very Low Very Low Very Low
Angina 6 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 62 100.00 Very High Very High Very High
Familial Combined Hyperlipidemia 127 99.90 Very High Very High Very High
Cardiovascular Disease 101 97.28 Very High Very High Very High
Cancer 2 94.44 High High
Xanthomatosis 1 92.32 High High
Pancreatitis 2 90.84 High High
Abdominal Pain 1 90.04 High High
Hyperlipidemia 9 88.76 High High
Chronic Disease 1 88.24 High High
Weight Loss 3 87.16 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The desirable level for TGs is defined as <200, moderate risk as 200–400, and high risk as ?
Gene_expression (level) of TGs
1) Confidence 0.22 Published 2009 Journal Trials Section Body Doc Link PMC2656492 Disease Relevance 0.93 Pain Relevance 0.04
Some investigators argued that introduction of both HDL-C and TGs as independent covariates in a model is inappropriate owing to multicollinearity and an intimate correlation between these variables in lipid metabolism [64].
Gene_expression (introduction) of TGs associated with disorder of lipid metabolism
2) Confidence 0.20 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2949857 Disease Relevance 0.75 Pain Relevance 0
LDL-C was calculated from the serum TC, TGs, and HDL-C concentrations expressed in mg/dl using Friedwald formula [38] if TGs concentration is lower than 400 mg/dl.
Gene_expression (expressed) of TGs associated with disorder of lipid metabolism
3) Confidence 0.20 Published 2009 Journal Trials Section Body Doc Link PMC2656492 Disease Relevance 0.38 Pain Relevance 0
We followed-up a causal candidate gene for both FCHL and TGs, fatty acid desaturase 3 (FADS3), residing in the FADS1-2-3 locus, which was recently implicated for TGs in a meta-analysis of genome-wide association studies for lipids in Caucasians [38].
Gene_expression (residing) of TGs associated with familial combined hyperlipidemia
4) Confidence 0.13 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2730565 Disease Relevance 0.76 Pain Relevance 0
The LPLSer(447)X variant is associated with decreased levels of plasma TGs and increased HDL cholesterol concentrations compared with wild-type LPL.
Gene_expression (levels) of TGs in plasma associated with disorder of lipid metabolism
5) Confidence 0.07 Published 2009 Journal Curr. Opin. Mol. Ther. Section Abstract Doc Link 20072945 Disease Relevance 0.60 Pain Relevance 0.09

General Comments

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