INT165644

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Context Info
Confidence 0.44
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.65
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pde5a) signal transduction (Pde5a)
Anatomy Link Frequency
spinal cord 3
dorsal root ganglion 1
Pde5a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 2 99.84 Very High Very High Very High
Spinal cord 4 98.84 Very High Very High Very High
antiallodynic 2 97.80 Very High Very High Very High
Brush evoked pain 12 78.80 Quite High
Analgesic 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 2 99.36 Very High Very High Very High
Diabetes Mellitus 16 97.84 Very High Very High Very High
Polyuria 2 81.20 Quite High
Neuropathic Pain 12 78.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The possible antiallodynic effect of phosphodiesterase 5 inhibitor sildenafil and nitric oxide donor glyceryl trinitrate as well as the changes in phosphodiesterase 5A2 mRNA expression in dorsal root ganglion and spinal cord of allodynic diabetic rats was assessed.
Regulation (changes) of Transcription (expression) of phosphodiesterase 5A2 in spinal cord associated with ganglion cysts, dorsal root ganglion, diabetes mellitus, antiallodynic and spinal cord
1) Confidence 0.44 Published 2010 Journal Eur. J. Pharmacol. Section Abstract Doc Link 20079349 Disease Relevance 0.83 Pain Relevance 0.46
The possible antiallodynic effect of phosphodiesterase 5 inhibitor sildenafil and nitric oxide donor glyceryl trinitrate as well as the changes in phosphodiesterase 5A2 mRNA expression in dorsal root ganglion and spinal cord of allodynic diabetic rats was assessed.
Regulation (changes) of in dorsal root ganglion Transcription (expression) of phosphodiesterase 5A2 in spinal cord associated with ganglion cysts, dorsal root ganglion, diabetes mellitus, antiallodynic and spinal cord
2) Confidence 0.15 Published 2010 Journal Eur. J. Pharmacol. Section Abstract Doc Link 20079349 Disease Relevance 0.83 Pain Relevance 0.46

General Comments

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