INT165724

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Context Info
Confidence 0.24
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.65
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Bdkrb1, Adora1) plasma membrane (Bdkrb1, Adora1) signal transducer activity (Bdkrb1, Adora1)
endoplasmic reticulum (Adora1)
Bdkrb1 (Mus musculus)
Adora1 (Mus musculus)
Pain Link Frequency Relevance Heat
B1 receptor 1 100.00 Very High Very High Very High
Hyperalgesia 1 98.28 Very High Very High Very High
Inflammation 1 93.56 High High
antagonist 2 93.52 High High
agonist 1 85.04 High High
tolerance 2 75.00 Quite High
bradykinin 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Diabetes Mellitus 11 100.00 Very High Very High Very High
Disease 1 99.40 Very High Very High Very High
Hyperalgesia 1 98.28 Very High Very High Very High
Neuropathic Pain 1 97.60 Very High Very High Very High
Ocular Toxicity (including Many Sub-types) 1 97.12 Very High Very High Very High
Renal Disease 1 96.60 Very High Very High Very High
Autoimmune Disease 1 94.32 High High
INFLAMMATION 1 93.56 High High
Hyperglycemia 3 80.80 Quite High
Impaired Glucose Tolerance 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Experimental evidence has shown that the bradykinin B1 receptor (BKB1-R) is involved in the development of type 1 diabetes and found to be upregulated alongside the disease.
bradykinin B1 receptor Positive_regulation (upregulated) of BKB1-R associated with diabetes mellitus, b1 receptor and disease
1) Confidence 0.24 Published 2010 Journal Neuropeptides Section Abstract Doc Link 20092893 Disease Relevance 1.65 Pain Relevance 0.43

General Comments

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