INT165775

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.79
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Darc) signal transducer activity (Darc)
Anatomy Link Frequency
synovial fluid 2
bladder 2
Darc (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 54 100.00 Very High Very High Very High
Inflammation 32 100.00 Very High Very High Very High
methotrexate 14 93.84 High High
Arthritis 50 83.92 Quite High
interstitial cystitis 2 50.00 Quite Low
cINOD 1 32.00 Quite Low
rheumatoid arthritis 9 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Rheumatism 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 31 100.00 Very High Very High Very High
Juvenile Chronic Polyarthritis 40 83.92 Quite High
Disease 10 77.72 Quite High
Interstitial Cystitis 2 51.24 Quite High
Arthritis 10 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 9 5.00 Very Low Very Low Very Low
Coagulation Disorder 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased transcription of inflammatory chemokines in synovial fluid cells
Positive_regulation (Increased) of Transcription (transcription) of chemokines in synovial fluid associated with chemokine and inflammation
1) Confidence 0.00 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526593 Disease Relevance 0.74 Pain Relevance 0.45
Quantitative real-time polymerase chain reaction confirmed increased mRNA expression of several genes in the bladder samples of patients with ulcerative interstitial cystitis, including CXCR3 binding chemokines (CXCL9, 10 and 11) and TNFSF14 (LIGHT).
Positive_regulation (increased) of Transcription (expression) of chemokines in bladder
2) Confidence 0.00 Published 2010 Journal J. Urol. Section Body Doc Link 20096889 Disease Relevance 0.05 Pain Relevance 0

General Comments

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