INT165810

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.60
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Phc1) DNA binding (Phc1)
Phc1 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 93 99.00 Very High Very High Very High
noradrenaline 15 98.48 Very High Very High Very High
Neurotransmitter 8 88.96 High High
imagery 5 75.88 Quite High
fluoxetine 1 67.28 Quite High
antagonist 2 54.64 Quite High
Nucleus accumbens 6 5.00 Very Low Very Low Very Low
Ventral tegmentum 3 5.00 Very Low Very Low Very Low
Eae 2 5.00 Very Low Very Low Very Low
Catecholamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 30 97.68 Very High Very High Very High
Cognitive Disorder 11 83.60 Quite High
Lumbar Puncture Related Headaches 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indirect support for MPH¬ís noradrenergic actions also comes from the finding that ADHD symptoms can be recreated by blocking ?
Positive_regulation (support) of MPH Binding (Indirect) of associated with attention deficit hyperactivity disorder
1) Confidence 0.08 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2701285 Disease Relevance 0.60 Pain Relevance 0.55
In conclusion, drug-drug interactions with MPH are likely mediated via CES1 inhibition as a result of concomitant drug therapies.
Positive_regulation (mediated) of MPH Binding (interactions) of
2) Confidence 0.06 Published 2010 Journal Toxicology Section Abstract Doc Link 20097249 Disease Relevance 0 Pain Relevance 0.07

General Comments

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