INT165844

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (ATF4, HSP90AB1) unfolded protein binding (HSP90AB1) nucleoplasm (ATF4)
mitochondrion (HSP90AB1) intracellular (HSP90AB1) DNA binding (ATF4)
Anatomy Link Frequency
embryonic kidney 1
ATF4 (Homo sapiens)
HSP90AB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 6 100.00 Very High Very High Very High
agonist 1 77.60 Quite High
Opioid 1 73.36 Quite High
Disease Link Frequency Relevance Heat
Neuroblastoma 1 92.84 High High
Shock 3 87.52 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Whole-genome tiling array analysis revealed that cAMP response element-binding protein, an important mediator for cellular adaptation to morphine, associated with the proximal promoter of Hsp90AB1 not only in SK-N-SH cells but also in rat PC12 and human embryonic kidney cells.
cAMP response element-binding protein Binding (associated) of Hsp90AB1 in embryonic kidney associated with morphine
1) Confidence 0.15 Published 2010 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 20100459 Disease Relevance 0.34 Pain Relevance 0.61

General Comments

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