INT165847

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Context Info
Confidence 0.60
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (HSP90AB1) protein folding (HSP90AB1) cytosol (HSP90AB1)
mitochondrion (HSP90AB1) intracellular (HSP90AB1) response to stress (HSP90AB1)
HSP90AB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 6 99.12 Very High Very High Very High
agonist 1 68.44 Quite High
Opioid 1 64.20 Quite High
Disease Link Frequency Relevance Heat
Neuroblastoma 1 83.68 Quite High
Shock 3 78.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hsp90AB1 transcript and protein levels increased significantly during morphine treatment, and co-application of geldanamycin (0.1-10 nM) effectively suppressed the increase in forskolin-activated adenylate cyclase activation by 56%.
Positive_regulation (increased) of Hsp90AB1 transcript associated with morphine
1) Confidence 0.60 Published 2010 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 20100459 Disease Relevance 0.31 Pain Relevance 0.60

General Comments

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