INT165919

Context Info Confidence 0.16 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.55 Pain Relevance 0.23

cytoplasm (Tlr4, Nfkb1) signal transduction (Tlr4, Nfkb1) mitochondrion (Nfkb1) intracellular (Tlr4) DNA binding (Nfkb1) protein complex (Nfkb1)

Anatomy Link Frequency neutrophil 2 Tlr4 (Mus musculus) Nfkb1 (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 9 91.08 antagonist 1 75.84 cINOD 1 46.28

Disease Link Frequency Relevance Heat Apoptosis 6 98.20 INFLAMMATION 7 91.08

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Although LPS induced NF-kappaB activation, which was blocked by rolipram, NF-kappaB inhibitors did not promote resolution of neutrophil accumulation in this model.

LPS Positive_regulation (induced) of Positive_regulation (activation) of NF-kappaB in neutrophil

1) Confidence 0.16 Published 2010 Journal J. Leukoc. Biol. Section Abstract Doc Link 20103769 Disease Relevance 0.55 Pain Relevance 0.23

General Comments

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