INT165962

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Context Info
Confidence 0.39
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.47
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Vim) structural molecule activity (Vim) plasma membrane (Vim)
cytoskeleton (Vim) nucleus (Vim) biological_process (Vim)
Anatomy Link Frequency
head 1
articular cartilage 1
Vim (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Eae 5 89.92 High High
Central grey 6 87.88 High High
Osteoarthritis 2 83.36 Quite High
Pain 4 79.20 Quite High
Hyperalgesia 1 78.72 Quite High
allodynia 1 78.04 Quite High
Sciatic nerve 2 75.00 Quite High
glial activation 1 75.00 Quite High
Neuropathic pain 1 58.08 Quite High
neuralgia 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Injury 6 89.92 High High
Urological Neuroanatomy 6 87.88 High High
Osteoarthritis 3 83.36 Quite High
Hypertrophy 14 79.28 Quite High
Pain 4 79.20 Quite High
Hyperalgesia 1 78.72 Quite High
Neuropathic Pain 2 78.04 Quite High
Obesity 6 50.00 Quite Low
Aging 22 45.60 Quite Low
Disease 2 37.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GeneChips, RT-PCR and Western blotting revealed the select up-regulation in translation and transcription of glial fibrillary acidic protein (GFAP) and Vimentin in rats with Persistent Disability.
Transcription (transcription) of Vimentin
1) Confidence 0.39 Published 2010 Journal Neuroscience Section Abstract Doc Link 20109535 Disease Relevance 1.31 Pain Relevance 0.97
In Figs. 8A and B, the filled symbols (and solid lines) show the relationship between the abundance of mRNA for types 1 and 3 collagens and the abundance of vimentin mRNA in young animals (each point corresponds to different animal or region – SAN head, SAN tail, or atrial muscle); there is a significant correlation as expected.
Transcription (abundance) of vimentin mRNA in head
2) Confidence 0.28 Published 2010 Journal Journal of Molecular and Cellular Cardiology Section Body Doc Link PMC2845824 Disease Relevance 0 Pain Relevance 0
Furthermore, vimentin (VIM) mRNA levels were higher in NP versus articular cartilage.
Transcription (levels) of vimentin in articular cartilage
3) Confidence 0.22 Published 2008 Journal The Open Orthopaedics Journal Section Abstract Doc Link PMC2687122 Disease Relevance 0.16 Pain Relevance 0.04
In Figs. 8A and B, the open symbols (and dashed lines) show that there is still a significant correlation between the abundance of collagen and vimentin mRNAs in the old animals, but the relationship is depressed as compared to that in the young animals.
Transcription (abundance) of vimentin
4) Confidence 0.19 Published 2010 Journal Journal of Molecular and Cellular Cardiology Section Body Doc Link PMC2845824 Disease Relevance 0 Pain Relevance 0

General Comments

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