INT165984

Context Info Confidence 0.04 First Reported 2010 Last Reported 2010 Negated 0 Speculated 1 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.16 Pain Relevance 0

signal transduction (TNFRSF11B) extracellular region (TNFRSF11B) proteinaceous extracellular matrix (TNFRSF11B) plasma membrane (PTGER1) extracellular matrix organization (TNFRSF11B) signal transducer activity (PTGER1)

Anatomy Link Frequency chondrocytes 2 PTGER1 (Homo sapiens) TNFRSF11B (Homo sapiens)

Pain Link Frequency Relevance Heat Osteoarthritis 5 50.00 cINOD 1 5.00

Disease Link Frequency Relevance Heat Osteoarthritis 4 82.16 INFLAMMATION 2 50.00 Knee Osteoarthritis 1 50.00

Sentences Mentioned In

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Anatomy

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We also used human OA chondrocytes to examine the effects of PGE(2) on OPG/RANKL synthesis, examining which surface receptors were affected by PGE(2).

PGE Spec (examine) Regulation (effects) of Gene_expression (synthesis) of OPG in chondrocytes

1) Confidence 0.04 Published 2010 Journal Arthritis Rheum. Section Body Doc Link 20112374 Disease Relevance 0.16 Pain Relevance 0

General Comments

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