INT165985

Context Info Confidence 0.03 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.12 Pain Relevance 0

signal transduction (TNFRSF11B) extracellular region (TNFRSF11B) proteinaceous extracellular matrix (TNFRSF11B) plasma membrane (PTGER1) extracellular matrix organization (TNFRSF11B) signal transducer activity (PTGER1)

PTGER1 (Homo sapiens) TNFRSF11B (Homo sapiens)

Pain Link Frequency Relevance Heat Osteoarthritis 5 50.00 cINOD 1 5.00

Disease Link Frequency Relevance Heat Osteoarthritis 4 61.56 INFLAMMATION 2 50.00 Knee Osteoarthritis 1 50.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Only EP2/EP4 agonists reproduced the effects of PGE(2) on OPG and RANKL induction.

PGE Regulation (effects) of Positive_regulation (induction) of OPG

1) Confidence 0.03 Published 2010 Journal Arthritis Rheum. Section Body Doc Link 20112374 Disease Relevance 0.12 Pain Relevance 0

General Comments

This test has worked.