INT166019

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NFKBIA) plasma membrane (NFKBIA) nucleus (NFKBIA)
enzyme binding (NFKBIA) transcription factor binding (NFKBIA) cytoplasm (NFKBIA)
NFKBIA (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 11 99.06 Very High Very High Very High
COX-2 inhibitor 2 81.96 Quite High
cINOD 2 80.12 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 4 95.32 Very High Very High Very High
Squamous Cell Carcinoma 3 84.24 Quite High
Cancer 3 77.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Data of Western blot further demonstrated that aspirin treatment caused activation of caspases, down-regulation of Mcl-1 protein, dephosphorylation of ERK-1/2 and AKT, and also IkappaB-alpha proteolysis-dependent NF-kappaB activation in YD-8 cells.
Regulation (regulation) of Gene_expression (proteolysis) of IkappaB-alpha associated with aspirin
1) Confidence 0.05 Published 2010 Journal Toxicol In Vitro Section Abstract Doc Link 20116423 Disease Relevance 0.64 Pain Relevance 0.65

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox