INT166086

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Context Info
Confidence 0.28
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (Hsp90aa1) intracellular (Hsp90aa1) protein complex (Hsp90aa1)
cytoplasm (Hsp90aa1) cytosol (Hsp90aa1) protein folding (Hsp90aa1)
Anatomy Link Frequency
body 1
Hsp90aa1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fluoxetine 6 95.98 Very High Very High Very High
Potency 1 88.08 High High
antidepressant 2 79.48 Quite High
dexamethasone 1 78.80 Quite High
Disease Link Frequency Relevance Heat
Stress 3 83.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fluoxetine treatment (5mg/kg body mass, 21day, intraperitoneally) induced a decrease in B(max) and in the amount of Hsp70 co-immunoprecipitated with the glucocorticoid receptor only in males, and stimulated the association of the receptor with Hsp90 in females.
Hsp90 Binding (association) of in body associated with fluoxetine
1) Confidence 0.28 Published 2010 Journal Eur. J. Pharmacol. Section Abstract Doc Link 20122922 Disease Relevance 0.08 Pain Relevance 0.60

General Comments

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