INT166099

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Context Info
Confidence 0.41
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.52
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP9) extracellular space (MMP9) extracellular region (MMP9)
proteinaceous extracellular matrix (MMP9) extracellular matrix organization (MMP9) protein complex (MMP9)
Anatomy Link Frequency
endothelial cell 1
MMP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 16 100.00 Very High Very High Very High
cytokine 3 100.00 Very High Very High Very High
Inflammatory response 1 83.60 Quite High
Inflammation 3 75.00 Quite High
qutenza 2 25.00 Low Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 83.24 Quite High
Dermatitis 1 75.00 Quite High
Adhesions 9 63.84 Quite High
Metastasis 17 63.44 Quite High
Cancer 31 61.72 Quite High
Prostate Cancer 40 57.56 Quite High
Cytomegalovirus Infection 3 39.20 Quite Low
Injury 14 5.00 Very Low Very Low Very Low
Hypercalcemia 5 5.00 Very Low Very Low Very Low
Skin Cancer 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found an increase in an active form of MMP-9 in PC3 cells.
Phosphorylation (form) of MMP-9
1) Confidence 0.41 Published 2007 Journal Mol Cancer Section Body Doc Link PMC1828067 Disease Relevance 0.24 Pain Relevance 0.03
Capsiate inhibited UVB-induced cyclooxygenase-2 (COX-2) expression, extracellular signal-related kinase 1/2 phosphorylation, nuclear translocation of NF-kappaB, and the expression of proinflammatory cytokines and potent angiogenic factors, including vascular endothelial cell growth factor and matrix metalloproteinase-2 (MMP-2) and MMP-9.
Phosphorylation (phosphorylation) of MMP-9 in endothelial cell associated with metalloproteinase and cytokine
2) Confidence 0.07 Published 2010 Journal Free Radic. Biol. Med. Section Abstract Doc Link 20123015 Disease Relevance 0.28 Pain Relevance 0.26

General Comments

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