INT166103

Context Info Confidence 0.43 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.24 Pain Relevance 0.56

protein folding (TBCE) cytoskeleton (TBCE) cytoplasm (TBCE)

Anatomy Link Frequency red blood cell 2 TBCE (Homo sapiens)

Pain Link Frequency Relevance Heat Paracetamol 7 99.98

Disease Link Frequency Relevance Heat Injury 2 85.44 Adhesions 1 84.88 Hepatotoxicity 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The further aggravation of APAP-induced LSEC disturbance upon depletion of KCs correlated with increased hepatic vascular permeability and red blood cell accumulation.

Positive_regulation (induced) of Negative_regulation (depletion) of KCs in red blood cell associated with paracetamol

1) Confidence 0.43 Published 2010 Journal Toxicol. Lett. Section Abstract Doc Link 20123118 Disease Relevance 0.24 Pain Relevance 0.56

General Comments

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