INT166108

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Context Info
Confidence 0.64
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 3.58
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNFSF10) extracellular space (TNFSF10) extracellular region (TNFSF10)
cell-cell signaling (TNFSF10)
Anatomy Link Frequency
joints 1
temporomandibular joint 1
TNFSF10 (Homo sapiens)
Pain Link Frequency Relevance Heat
Snapping jaw 1 99.52 Very High Very High Very High
Inflammation 55 93.28 High High
agonist 28 91.52 High High
Arthritis 20 88.12 High High
antagonist 25 73.48 Quite High
rheumatoid arthritis 34 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
cINOD 5 5.00 Very Low Very Low Very Low
qutenza 3 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Temporomandibular Joint Syndrome 1 99.52 Very High Very High Very High
Apoptosis 419 99.28 Very High Very High Very High
Cancer 333 95.92 Very High Very High Very High
Necrosis 8 95.68 Very High Very High Very High
INFLAMMATION 51 93.28 High High
Arthritis 50 88.12 High High
Renal Cancer 2 85.76 High High
Reprotox - General 1 4 84.20 Quite High
Toxicity 15 83.60 Quite High
Leukemia 7 82.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Occurrence and regional distribution of TRAIL and DR5 on temporomandibular joint discs: comparison of disc derangement with and without reduction.
Localization (distribution) of TRAIL in temporomandibular joint associated with snapping jaw
1) Confidence 0.64 Published 2010 Journal Oral Surg Oral Med Oral Pathol Oral Radiol Endod Section Title Doc Link 20123409 Disease Relevance 0.48 Pain Relevance 0.10
To test the potential in vivo biological efficacy of rTRAIL, 5 and 20 ?
Localization (efficacy) of rTRAIL
2) Confidence 0.63 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526576 Disease Relevance 0.24 Pain Relevance 0.10
Histological examination of H&E stained cartilage sections from rTRAIL treated and saline control joints showed cartilage destruction due to IL-1?
Localization (sections) of rTRAIL in joints
3) Confidence 0.63 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526576 Disease Relevance 1.01 Pain Relevance 0.05
-catenin by TRAIL, membranous localization of ?
Localization (localization) of TRAIL
4) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2908545 Disease Relevance 0.50 Pain Relevance 0
Cells were treated with TRAIL for ?
Localization (treated) of TRAIL
5) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2908545 Disease Relevance 0.44 Pain Relevance 0
As well, DR5 upregulation contributes to the sensitization of TRAIL-induced
Localization (sensitization) of TRAIL
6) Confidence 0.15 Published 2008 Journal PPAR Research Section Body Doc Link PMC2442903 Disease Relevance 0.90 Pain Relevance 0.08

General Comments

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