INT166153

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Context Info
Confidence 0.36
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.78
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Pik3r1, Ccr9) plasma membrane (Pik3r1, Ccr9) intracellular (Pik3r1)
protein complex (Pik3r1) signal transducer activity (Ccr9) cytoplasm (Pik3r1)
Pik3r1 (Mus musculus)
Ccr9 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 1 85.88 High High
palliative 1 73.68 Quite High
Disease Link Frequency Relevance Heat
Reprotox - General 1 7 93.16 High High
Apoptosis 2 82.28 Quite High
Cancer 2 76.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Significant downregulation of these CCR9-mediated antiapoptotic proteins in the presence of a PI3K inhibitor (wortmannin), further suggests that the antiapoptotic action of CCR9 is primarily regulated through PI3K.
PI3K Regulation (regulated) of Gene_expression (action) of CCR9
1) Confidence 0.36 Published 2010 Journal Int. J. Cancer Section Abstract Doc Link 20127861 Disease Relevance 0.78 Pain Relevance 0.12

General Comments

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