INT16622

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Context Info
Confidence 0.67
First Reported 1991
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 6
Total Number 10
Disease Relevance 5.20
Pain Relevance 1.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (PLXNA3) plasma membrane (PLXNA3) intracellular (PLXNA3)
Anatomy Link Frequency
body 1
PLXNA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 3 99.84 Very High Very High Very High
spinal inflammation 6 98.44 Very High Very High Very High
alcohol 201 98.20 Very High Very High Very High
Pain 5 77.28 Quite High
addiction 5 75.68 Quite High
opiate 12 67.28 Quite High
headache 2 66.36 Quite High
Inflammation 1 54.48 Quite High
Dismenorea 4 50.00 Quite Low
Potency 1 28.56 Quite Low
Disease Link Frequency Relevance Heat
Stress 98 99.90 Very High Very High Very High
Low Back Pain 6 98.44 Very High Very High Very High
Alcohol Intoxication 24 97.72 Very High Very High Very High
Aging 5 97.60 Very High Very High Very High
Acne 1 97.02 Very High Very High Very High
Nicotine Addiction 2 94.96 High High
Infection 80 89.84 High High
Adenoma 1 87.36 High High
Bone Fracture 1 86.88 High High
Cognitive Disorder 6 81.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSION: A low-fat vegetarian diet was associated with increased serum sex-hormone binding globulin concentration and reductions in body weight, dysmenorrhea duration and intensity, and premenstrual symptom duration.
Positive_regulation (increased) of sex in body
1) Confidence 0.67 Published 2000 Journal Obstet Gynecol Section Body Doc Link 10674588 Disease Relevance 0 Pain Relevance 0
Acne is well controlled, as would be expected from its inhibition of ovulation, antiandrogenic activity and lack of attenuation of the estrogen-mediated increase in sex hormone binding globulin.
Positive_regulation (increase) of sex associated with acne
2) Confidence 0.67 Published 2002 Journal Eur J Contracept Reprod Health Care Section Abstract Doc Link 12659402 Disease Relevance 0.62 Pain Relevance 0.06
Serum sex hormone binding globulin was elevated.
Positive_regulation (elevated) of sex
3) Confidence 0.67 Published 2003 Journal South. Med. J. Section Abstract Doc Link 14513996 Disease Relevance 1.00 Pain Relevance 0.12
Our findings suggest a possible role of sex hormones in the physiopathogenesis of AS and offers a possible therapeutic alternative.
Spec (possible) Positive_regulation (role) of sex associated with spinal inflammation
4) Confidence 0.49 Published 1991 Journal J. Rheumatol. Section Abstract Doc Link 1843848 Disease Relevance 0.56 Pain Relevance 0.49
But free or bioavailable oestrogens may decline due to an increase in sex hormone binding globulin.
Positive_regulation (increase) of sex
5) Confidence 0.45 Published 2003 Journal Ann. Endocrinol. (Paris) Section Abstract Doc Link 12773948 Disease Relevance 0.73 Pain Relevance 0.10
In closing, this study indicates that acute stress can enhance sex differences in risk taking behavior.
Positive_regulation (enhance) of sex associated with stress
6) Confidence 0.09 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2698212 Disease Relevance 0.50 Pain Relevance 0
IDUs were more likely than non-IDUs to report having sex while the participant, his or her partner, or both were drunk or high (i.e. having sex when high on drugs or alcohol) (Table 1).
Positive_regulation (having) of sex associated with alcohol intoxication and alcohol
7) Confidence 0.03 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2988741 Disease Relevance 0.91 Pain Relevance 0.05
The latter was retained in the multivariate model for non-IDUs due to its removal changing the aOR for sex while high by > 10%.
Positive_regulation (changing) of sex
8) Confidence 0.03 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2988741 Disease Relevance 0.05 Pain Relevance 0.31
However, alcohol use is widely accepted in Russia and studies have shown that drinking is often used as a facilitator of sex and as a symbol of masculinity in the Russian culture [35].
Positive_regulation (facilitator) of sex associated with alcohol
9) Confidence 0.03 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2988741 Disease Relevance 0.22 Pain Relevance 0.42
Studies conducted among Russian non-drug using youth indicate that in recent years levels of unprotected sex have increased, age of sexual debut has decreased, rates of partner change have increased, and sexual activity under the influence of alcohol has become more prevalent among the general population, increasing the potential for the transmission of sexually transmitted infections (STIs) overall [18-20].
Positive_regulation (increased) of sex associated with infection and alcohol
10) Confidence 0.03 Published 2010 Journal BMC Public Health Section Body Doc Link PMC2988741 Disease Relevance 0.60 Pain Relevance 0.15

General Comments

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