INT166240

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Context Info
Confidence 0.51
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.03
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Cav1) mitochondrion (Cav1) Golgi apparatus (Cav1)
endoplasmic reticulum (Cav1) intracellular (Cav1) protein complex (Cav1)
Anatomy Link Frequency
bowel 2
Cav1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 6 100.00 Very High Very High Very High
Pain 2 100.00 Very High Very High Very High
IPN 2 99.72 Very High Very High Very High
Calcium channel 3 50.00 Quite Low
spastic colon 2 50.00 Quite Low
Inflammatory response 1 14.32 Low Low
antagonist 12 5.00 Very Low Very Low Very Low
Serotonin 5 5.00 Very Low Very Low Very Low
fluoxetine 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Inflammatory Pain 2 99.72 Very High Very High Very High
Pulmonary Hypertension 150 98.68 Very High Very High Very High
Hypertrophy 36 98.24 Very High Very High Very High
Functional Bowel Disorder 2 50.00 Quite Low
Diarrhoea 2 50.00 Quite Low
Death 2 40.12 Quite Low
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

1 32.44 Quite Low
INFLAMMATION 8 14.32 Low Low
Hypoxia 7 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To study whether in vivo modulation of Cav-1 expression could affect the development of PAH and RV hypertrophy, rats were injected with MCT, followed by a daily injection of (1) saline, (2) a peptide corresponding to the homeodomain of the Drosophila transcription factor antennapedia (AP; 2.5?
Regulation (modulation) of Gene_expression (expression) of Cav-1 associated with hypertrophy and pulmonary hypertension
1) Confidence 0.51 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2843902 Disease Relevance 0.85 Pain Relevance 0
CONCLUSIONS: The traditional modeling of irritable bowel syndrome in rats alters the expression of Cav1.2 and Cav1.3.
Regulation (alters) of Gene_expression (expression) of Cav1 in bowel
2) Confidence 0.27 Published 2009 Journal Zhonghua Yi Xue Za Zhi Section Body Doc Link 20137275 Disease Relevance 0 Pain Relevance 0
Changes in gene expression of caveolin-1 after inflammatory pain using quantitative real-time PCR.
Regulation (Changes) of Gene_expression (expression) of caveolin-1 associated with inflammation and ipn
3) Confidence 0.27 Published 2010 Journal Methods Mol. Biol. Section Title Doc Link 20300998 Disease Relevance 0.18 Pain Relevance 0.43

General Comments

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