INT166268

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.79
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Lcp1) plasma membrane (Lcp1) cytoskeleton (Lcp1)
cytoplasm (Lcp1)
Anatomy Link Frequency
blood 1
synovial fluid 1
colon 1
Lcp1 (Mus musculus)
Pain Link Frequency Relevance Heat
abdominal pain 2 68.00 Quite High
rheumatoid arthritis 58 54.60 Quite High
Inflammation 9 51.20 Quite High
corticosteroid 8 5.00 Very Low Very Low Very Low
methotrexate 8 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
cINOD 6 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cytomegalovirus Infection 102 100.00 Very High Very High Very High
Infection 25 99.40 Very High Very High Very High
Intussusception 6 93.20 High High
Enterocolitis 1 75.00 Quite High
Colitis 1 72.20 Quite High
Abdominal Pain 2 68.00 Quite High
Crigler-najjar Syndrome 1 57.28 Quite High
Rheumatoid Arthritis 60 54.60 Quite High
Cancer 3 52.80 Quite High
Disease 39 52.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Whenever possible a PCR for CMV in colon biopsies should be carried out to detect an intestinal CMV infection because as shown in our case results for immunohistopathology and CMV pp65 can be negative despite a chronic infection.
Positive_regulation (results) of pp65 in colon associated with cytomegalovirus infection and infection
1) Confidence 0.49 Published 2010 Journal Z Gastroenterol Section Abstract Doc Link 20140843 Disease Relevance 1.89 Pain Relevance 0.15
production could be provoked from CD4+CD28null T cells in peripheral blood and synovial fluid, after stimulation by the HCMV-derived pp65 and immediate early antigens.
Positive_regulation (derived) of pp65 in synovial fluid associated with cytomegalovirus infection
2) Confidence 0.06 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2212553 Disease Relevance 0.45 Pain Relevance 0.03
production could be provoked from CD4+CD28null T cells in peripheral blood and synovial fluid, after stimulation by the HCMV-derived pp65 and immediate early antigens.
Positive_regulation (derived) of pp65 in blood associated with cytomegalovirus infection
3) Confidence 0.02 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2212553 Disease Relevance 0.45 Pain Relevance 0.03

General Comments

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