INT1663

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.55
First Reported 1979
Last Reported 2000
Negated 1
Speculated 2
Reported most in Abstract
Documents 12
Total Number 13
Disease Relevance 2.73
Pain Relevance 12.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (Nrm) nucleus (Nrm)
Anatomy Link Frequency
neurons 2
cerebral cortex 1
nucleus 1
midbrain 1
interneurons 1
Nrm (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Raphe magnus 136 100.00 Very High Very High Very High
Glutamate 15 100.00 Very High Very High Very High
cerebral cortex 12 100.00 Very High Very High Very High
agonist 7 100.00 Very High Very High Very High
excitatory amino acid 2 100.00 Very High Very High Very High
descending inhibitory control 1 100.00 Very High Very High Very High
noradrenaline 9 99.98 Very High Very High Very High
nociceptor 10 99.90 Very High Very High Very High
Acupuncture 12 99.24 Very High Very High Very High
Antinociceptive 3 99.24 Very High Very High Very High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 23 100.00 Very High Very High Very High
Nociception 20 100.00 Very High Very High Very High
Pain 12 95.92 Very High Very High Very High
Hypoalagesia 1 93.44 High High
Hyperalgesia 2 75.00 Quite High
Peripheral Arterial Disease 2 5.00 Very Low Very Low Very Low
Cough 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have further demonstrated that analgesic effects of Sm II stimulation were achieved by the modulation of Sm II on NRM, via NAc and NHa closely related to limbic-midbrain system, and with NRM descending inhibitory pathways through dorsal lateral fasciculus (DLF) in the level of spinal cord. 4.
Regulation (modulation) of NRM in midbrain associated with raphe magnus, analgesic, midbrain and spinal cord
1) Confidence 0.55 Published 1996 Journal Zhen Ci Yan Jiu Section Abstract Doc Link 9387347 Disease Relevance 0.42 Pain Relevance 1.85
Previous reports from this laboratory suggest that noradrenergic (NA) neurons modulate the activity of NRM neurons.
Regulation (modulate) of NRM in neurons associated with raphe magnus
2) Confidence 0.48 Published 1985 Journal Brain Res. Section Abstract Doc Link 2859092 Disease Relevance 0.34 Pain Relevance 0.88
The present study examined the effects on nociceptive threshold of microinjection of a wide dose range (0.1-150 ng) of the GABAB receptor agonist, baclofen hydrochloride (BAC), in the NRM, NGCp alpha or the nucleus reticularis giganto-cellularis (NGC).
Spec (examined) Regulation (effects) of NRM in nucleus associated with nociception, raphe magnus and agonist
3) Confidence 0.45 Published 1995 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 7562560 Disease Relevance 0.17 Pain Relevance 0.64
Further, we studied whether these cholinergic agonists and noradrenaline modulate the activity of the identical NRM neurons.
Spec (whether) Regulation (modulate) of NRM in neurons associated with raphe magnus, noradrenaline and agonist
4) Confidence 0.24 Published 2000 Journal Hokkaido Igaku Zasshi Section Abstract Doc Link 10976405 Disease Relevance 0.15 Pain Relevance 1.04
We postulated that the analgesic action of supraspinally administered opiates results from increased descending inhibitory control of the NRM.
Regulation (control) of NRM associated with raphe magnus, analgesic, descending inhibitory control and opiate
5) Confidence 0.24 Published 1995 Journal Anesth. Analg. Section Abstract Doc Link 7726430 Disease Relevance 0.09 Pain Relevance 0.65
Microinjection of 0.35 micrograms of morphine, a dose which has small and unreliable antinociceptive effects in awake animals, had little effect on the activity of NRM cells.
Neg (little) Regulation (effect) of NRM associated with raphe magnus, antinociceptive and morphine
6) Confidence 0.24 Published 1983 Journal Brain Res. Section Abstract Doc Link 6616214 Disease Relevance 0 Pain Relevance 0.74
In the studies reported here, the activity of the cells in the PAG was increased by microinjection of glutamate in this area and its effect on both the activity of single cells in the NRM and on a flexion reflex elicited by noxious heat was measured.
Regulation (effect) of NRM associated with raphe magnus, glutamate and central grey
7) Confidence 0.23 Published 1979 Journal Brain Res. Section Abstract Doc Link 223721 Disease Relevance 0.44 Pain Relevance 0.96
[The modulation of cerebral cortex and subcortical nuclei on NRM and their role in acupuncture analgesia].
Regulation (modulation) of NRM in cerebral cortex associated with nociceptor, acupuncture, cerebral cortex and analgesia
8) Confidence 0.21 Published 1996 Journal Zhen Ci Yan Jiu Section Title Doc Link 9387347 Disease Relevance 0.20 Pain Relevance 1.18
It was also demonstrated the Sm I could modulate NRM by mediation of NCa of extrapyramidal system enhancing EA analgesia.
Regulation (modulate) of NRM associated with raphe magnus, electroacupuncture and analgesia
9) Confidence 0.21 Published 1996 Journal Zhen Ci Yan Jiu Section Abstract Doc Link 9387347 Disease Relevance 0.26 Pain Relevance 1.88
The suppressive effect of PAG and NRM stimulation on the reflexes and NST reflex interneurons could be reduced by the intravenous administration of naloxone.
Regulation (effect) of NRM in interneurons associated with raphe magnus, narcan and urological neuroanatomy
10) Confidence 0.20 Published 1981 Journal Brain Res. Section Abstract Doc Link 6266582 Disease Relevance 0.65 Pain Relevance 0.78
The effect of excitatory amino acid glutamate (GLU) administration into NRM (GLU-NRM) was tested on all 69 cells.
Regulation (effect) of NRM associated with raphe magnus, glutamate and excitatory amino acid
11) Confidence 0.13 Published 1993 Journal Pain Section Abstract Doc Link 8309708 Disease Relevance 0 Pain Relevance 0.74
The effect of excitatory amino acid glutamate (GLU) administration into NRM (GLU-NRM) was tested on all 69 cells.
Regulation (effect) of NRM associated with raphe magnus, glutamate and excitatory amino acid
12) Confidence 0.13 Published 1993 Journal Pain Section Abstract Doc Link 8309708 Disease Relevance 0 Pain Relevance 0.73
Iontophoretic application of Met5-enkephalin near the terminal region did not affect resting terminal excitability but reduced the effectiveness of NRM stimulation to increase terminal excitability.
Regulation (effectiveness) of NRM associated with raphe magnus and enkephalin
13) Confidence 0.13 Published 1983 Journal Neurosci. Lett. Section Abstract Doc Link 6310455 Disease Relevance 0 Pain Relevance 0.66

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox