INT166300

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Context Info
Confidence 0.39
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.63
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Adrbk1, Gpbar1) plasma membrane (Gpbar1) kinase activity (Adrbk1)
signal transducer activity (Gpbar1) cytoplasm (Adrbk1)
Adrbk1 (Mus musculus)
Gpbar1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 5 96.24 Very High Very High Very High
Lasting pain 1 95.08 Very High Very High Very High
IPN 2 88.48 High High
Thermal hyperalgesia 1 75.60 Quite High
allodynia 1 72.72 Quite High
chemokine 1 64.32 Quite High
Hyperalgesia 7 53.68 Quite High
nociceptor 1 46.48 Quite Low
Spinal cord 3 25.00 Low Low
Pain 3 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 3 96.24 Very High Very High Very High
Pain 1 95.08 Very High Very High Very High
Inflammatory Pain 2 88.48 High High
Hyperalgesia 8 75.60 Quite High
Neuropathic Pain 2 72.72 Quite High
Cancer 1 25.00 Low Low
Necrosis 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GRK2 regulates cellular signaling by promoting G-protein-coupled receptor (GPCR) desensitization and direct interaction with downstream kinases including p38.
GRK2 Positive_regulation (promoting) of Negative_regulation (desensitization) of GPCR
1) Confidence 0.39 Published 2010 Journal J. Neurosci. Section Abstract Doc Link 20147541 Disease Relevance 0.63 Pain Relevance 0.58

General Comments

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