INT166381

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Context Info
Confidence 0.43
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0.73
Pain Relevance 2.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Gnb2l1) cytoskeleton (Gnb2l1) nucleus (Gnb2l1)
cell cycle (Gnb2l1) cytoplasm (Gnb2l1)
Anatomy Link Frequency
striatum 1
frontal cortex 1
Gnb2l1 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropeptide 6 100.00 Very High Very High Very High
Morphine 27 99.96 Very High Very High Very High
Hippocampus 6 97.16 Very High Very High Very High
Nucleus accumbens 9 96.52 Very High Very High Very High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 9 99.44 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was found that morphine reexposured mice showed a decreased RACK1 level in the frontal cortex, striatum and an increased RACK1 level in hippocampus and NAcc, but this effect was reversed after administration of RACK1.
Negative_regulation (decreased) of RACK1 in striatum associated with nucleus accumbens, urological neuroanatomy, hippocampus and morphine
1) Confidence 0.43 Published 2009 Journal Arch Ital Biol Section Abstract Doc Link 20162862 Disease Relevance 0.24 Pain Relevance 0.93
RACK1, a potential target to decrease morphine reward in mice.
Negative_regulation (decrease) of RACK1 associated with neuropeptide and morphine
2) Confidence 0.42 Published 2009 Journal Arch Ital Biol Section Title Doc Link 20162862 Disease Relevance 0.25 Pain Relevance 0.83
It was found that morphine reexposured mice showed a decreased RACK1 level in the frontal cortex, striatum and an increased RACK1 level in hippocampus and NAcc, but this effect was reversed after administration of RACK1.
Negative_regulation (decreased) of RACK1 in frontal cortex associated with nucleus accumbens, urological neuroanatomy, hippocampus and morphine
3) Confidence 0.15 Published 2009 Journal Arch Ital Biol Section Abstract Doc Link 20162862 Disease Relevance 0.24 Pain Relevance 0.93

General Comments

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