INT166398

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Context Info
Confidence 0.46
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.83
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CDKN1B, CDKN1A) nucleoplasm (CDKN1B, CDKN1A) nucleus (CDKN1B, CDKN1A)
cell cycle (CDKN1B, CDKN1A) kinase activity (CDKN1B, CDKN1A) cytoplasm (CDKN1B, CDKN1A)
CDKN1B (Homo sapiens)
CDKN1A (Homo sapiens)
Pain Link Frequency Relevance Heat
Dynorphin 2 96.56 Very High Very High Very High
Morphine 2 94.72 High High
Kappa opioid receptor 4 93.04 High High
opioid receptor 2 83.28 Quite High
agonist 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Multiple Myeloma 4 90.52 High High
Malignant Neoplastic Disease 2 87.40 High High
Apoptosis 4 84.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
U50 488 produces a modest but significant decrease in viability associated with an arrest in the G0/G1 phase, but not antagonized by NorBNI and not associated with modulation of p21(Cip1), p27(Kip1) or p53 expression.
Kip1 Regulation (modulation) of Gene_expression (expression) of Cip1
1) Confidence 0.46 Published 2010 Journal J. Neuroimmunol. Section Abstract Doc Link 20163878 Disease Relevance 0.41 Pain Relevance 0.31
U50 488 produces a modest but significant decrease in viability associated with an arrest in the G0/G1 phase, but not antagonized by NorBNI and not associated with modulation of p21(Cip1), p27(Kip1) or p53 expression.
Kip1 Regulation (modulation) of Gene_expression (expression) of p21
2) Confidence 0.46 Published 2010 Journal J. Neuroimmunol. Section Abstract Doc Link 20163878 Disease Relevance 0.41 Pain Relevance 0.31

General Comments

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