INT166432

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.44
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.45
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Atp2a2) endoplasmic reticulum (Atp2a2) protein complex (Atp2a2)
Anatomy Link Frequency
ventricle 1
lumen 1
Atp2a2 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 3 91.64 High High
Kinase C 2 71.12 Quite High
cytokine 2 68.84 Quite High
addiction 1 35.36 Quite Low
Spinal cord 14 5.00 Very Low Very Low Very Low
medulla 8 5.00 Very Low Very Low Very Low
midbrain 4 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
Hippocampus 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertrophy 3 100.00 Very High Very High Very High
Apoptosis 10 78.52 Quite High
Stress 29 69.88 Quite High
Disease 26 50.32 Quite High
Motor Neuron Diseases 124 50.00 Quite Low
Bacillus Anthracis Infection 28 50.00 Quite Low
Repression 6 37.44 Quite Low
Toxicity 2 31.88 Quite Low
Pressure Volume 2 Under Development 3 24.76 Low Low
Pressure And Volume Under Development 13 18.12 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, training induced right ventricle hypertrophy in SERCA2 KO mice.
Positive_regulation (induced) of SERCA2 in ventricle associated with hypertrophy
1) Confidence 0.44 Published 2010 Journal J. Appl. Physiol. Section Abstract Doc Link 20167673 Disease Relevance 0.10 Pain Relevance 0.08
In SERCA2 FF mice, both VO2max and maximal running speed increased by training, while no changes occurred in the sedentary group.
Positive_regulation (increased) of SERCA2
2) Confidence 0.41 Published 2010 Journal J. Appl. Physiol. Section Abstract Doc Link 20167673 Disease Relevance 0.09 Pain Relevance 0.09
Our in vitro data revealed that cellular machineries responsible for cardiac relaxation such as SERCA and phospholamban were downregulated and upregulated, respectively, in response to lethal toxin exposure.
Positive_regulation (upregulated) of SERCA
3) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2954163 Disease Relevance 0 Pain Relevance 0
In addition, the upregulation of SERCA and the mitochondrial calcium transporters NCX1 and VDAC3, may result in excess calcium being transported out of the mitochondria and into the ER lumen, having the net effect of an increased [Ca2+] in the ER lumen and reduced [Ca2+] in the mitochondria.
Positive_regulation (upregulation) of SERCA in lumen
4) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844426 Disease Relevance 0.27 Pain Relevance 0.03
NCX1 and SERCA were selected for verification by Q-PCR, and were found to be upregulated by 25.75 fold (p<0.0001) and 1.66 fold (p?
Positive_regulation (upregulated) of SERCA
5) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2844426 Disease Relevance 0 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox