INT166630

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Context Info
Confidence 0.41
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0.88

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Golgi apparatus (Becn1) cytoplasmic membrane-bounded vesicle (Becn1) cell cycle (Becn1)
molecular_function (Becn1) protein complex (Becn1) cellular_component (Becn1)
Becn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 9 99.30 Very High Very High Very High
Hippocampus 2 92.80 High High
addiction 1 85.96 High High
Disease Link Frequency Relevance Heat
Neuroblastoma 2 91.16 High High
Targeted Disruption 1 90.00 High High
Injury 2 86.68 High High
Drug Dependence 1 85.96 High High
Death 1 81.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Morphine increases Beclin 1 expression and reduces the interaction between Beclin 1 and Bcl-2, thus releasing Beclin 1 for its pro-autophagic activity.
Negative_regulation (reduces) of Localization (releasing) of Beclin 1 associated with morphine
1) Confidence 0.41 Published 2010 Journal Autophagy Section Abstract Doc Link 20190558 Disease Relevance 0.51 Pain Relevance 0.88

General Comments

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