INT166702

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.62
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (Ier2) biological_process (Ier2) cytoplasm (Ier2)
Anatomy Link Frequency
livers 1
neutrophil 1
Ier2 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 4 99.68 Very High Very High Very High
Inflammation 2 92.32 High High
chemokine 2 90.88 High High
Migraine 5 75.00 Quite High
headache 1 62.56 Quite High
anesthesia 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 4 99.80 Very High Very High Very High
Adhesions 1 93.88 High High
INFLAMMATION 2 92.32 High High
Atrial Heart Septal Defects 1 76.56 Quite High
Patent Foramen Ovale 6 75.64 Quite High
Headache 6 75.00 Quite High
Cerebral Toxoplasmosis 4 75.00 Quite High
Congenital Anomalies 2 69.84 Quite High
Thrombophilia 1 34.00 Quite Low
Targeted Disruption 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
livers displayed downregulation of Egr-1, an immediate early growth response gene shown to be involved in the control of mitotic entry through the spindle assembly checkpoint [21].
Negative_regulation (downregulation) of immediate early growth response gene in livers
1) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2940888 Disease Relevance 0 Pain Relevance 0
Moreover, hypoxia markedly decreased T-lymphocyte IL-2 mRNA, a key cytokine responsible for B-cell proliferation and immunoglobulin secretion, and ischemic tissues demonstrated intravascular neutrophil accumulation, vascular damage, and increased vascular wall permeability.
Negative_regulation (decreased) of T-lymphocyte IL-2 mRNA in neutrophil associated with hypoxia and cytokine
2) Confidence 0.01 Published 2010 Journal Int. J. Neurosci. Section Abstract Doc Link 20199198 Disease Relevance 1.62 Pain Relevance 0.61

General Comments

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