INT166716

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.43
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.67
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ihh) peptidase activity (Ihh) extracellular region (Ihh)
plasma membrane (Ihh) embryo development (Ihh) cell-cell signaling (Ihh)
Ihh (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 2 99.56 Very High Very High Very High
Snapping jaw 4 98.56 Very High Very High Very High
dexamethasone 94 53.44 Quite High
cytokine 9 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 2 100.00 Very High Very High Very High
Temporomandibular Joint Syndrome 4 98.56 Very High Very High Very High
Sarcoma 4 95.76 Very High Very High Very High
Osteochondroma 40 90.00 High High
Cancer 16 66.24 Quite High
Multiple Hereditary Exostoses 45 50.00 Quite Low
Congenital Anomalies 6 38.56 Quite Low
Chondrosarcoma 19 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 17 5.00 Very Low Very Low Very Low
Syndrome 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ihh deficiency caused condylar disorganization and growth retardation and reduced polymorphic cell layer proliferation.
Negative_regulation (deficiency) of Ihh
1) Confidence 0.43 Published 2010 Journal J. Dent. Res. Section Abstract Doc Link 20200412 Disease Relevance 0.25 Pain Relevance 0.25
Probes for Indian hedgehog (Ihh), Tissue inhibitor of matrix metalloproteinase 4 (Timp4), Cyclin-dependent kinase inhibitor 1C (Cdkn1c, p57), Integrin beta like 1 protein (Itgbl1), GC receptor (Nr3c1), Integrin beta 1 (Itgb1) and Kruppel-like factor 15 (Klf15) were assayed using the TaqMan® gene expression assays in accordance with the manufacturers directions.
Negative_regulation (inhibitor) of Ihh associated with metalloproteinase
2) Confidence 0.32 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1929075 Disease Relevance 0 Pain Relevance 0.08
FGFR3 activation also leads to repression of IHh signalling [80,81,86].


Negative_regulation (repression) of IHh associated with repression
3) Confidence 0.09 Published 2004 Journal Hered Cancer Clin Pract Section Body Doc Link PMC2840003 Disease Relevance 0.42 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox