INT166810

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 2.16
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Casq1) Golgi apparatus (Casq1) molecular_function (Casq1)
response to stress (Casq1) cytoplasm (Casq1)
Anatomy Link Frequency
cardiomyocytes 1
Casq1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 1 84.92 Quite High
ischemia 8 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Morphine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 208 99.84 Very High Very High Very High
Muscle Disease 3 98.48 Very High Very High Very High
Muscle Weakness 1 86.36 High High
Myalgia 1 84.92 Quite High
Stress 24 69.04 Quite High
Apoptosis 100 66.96 Quite High
Myocardial Infarction 16 59.36 Quite High
Shock 4 55.44 Quite High
Death 16 48.72 Quite Low
Lymphatic System Cancer 4 43.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Considering that calsequestrin overexpression increases SR Ca2+ content by inhibition of RyRs,42 calsequestrin overexpression is also likely to contribute to intracellular Ca2+ overload.
Gene_expression (overexpression) of calsequestrin
1) Confidence 0.10 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2824862 Disease Relevance 0.38 Pain Relevance 0
Considering that calsequestrin overexpression increases SR Ca2+ content by inhibition of RyRs,42 calsequestrin overexpression is also likely to contribute to intracellular Ca2+ overload.
Gene_expression (overexpression) of calsequestrin
2) Confidence 0.10 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2824862 Disease Relevance 0.44 Pain Relevance 0
Our results showed increased expression of calsequestrin in hypoxia-reoxygenation condition (p < 0.05), but there was no significant change in response to exposure to thiopental.
Gene_expression (expression) of calsequestrin associated with hypoxia
3) Confidence 0.10 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2824862 Disease Relevance 0.29 Pain Relevance 0
We found that these inclusions were positive for calsequestrin and for the calsequestrin-binding protein junctin, as well as for caveolin 3.
Gene_expression (positive) of calsequestrin
4) Confidence 0.08 Published 2010 Journal Neuromuscul. Disord. Section Abstract Doc Link 20211563 Disease Relevance 0.34 Pain Relevance 0.08
However, mRNA levels of Na+-Ca2+ exchanger (NCX) and calsequestrin increased in hypoxia-reoxygenated cardiomyocytes.
Gene_expression (exchanger) of calsequestrin in cardiomyocytes associated with hypoxia
5) Confidence 0.08 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2824862 Disease Relevance 0.71 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox